Analytical Methods Validation

Bob McDowall has been involved in writing on analytical methods validation for many years, he has written several key papers on the subject. Find out more here...

Bob McDowall has been involved in writing on analytical methods validation for many years, he has written several key papers on the subject. Two articles can be downloaded from this site on general aspects of method validation and one on the debate on selectivity versus specificity, both these papers were co-authored with Jurgen Vessmann and Bengt Arne Persson from AstraZeneca in Mölndal, Sweden

Title needed - Article 1

Is your method specific or just selective? - Article 2

Method transfer is also an important factor when developing and writing analytical method reports. Bob has written a Questions of Quality paper from LC-GC Europe on method transfer that is available for download in PDF format.

Who developed this &”$!! method? - Article 3

For those students of trivia, there is a Questions of Quality article on how we set up autosampler sequences and the impact that this can have on the quality of the whole analytical run.

The next in line - Article

Consulting Services

McDowall Consulting offers the following services in the area of analytical method validation:

  • Training Course on analytical method validation covering the latest ICH and FDA guidance documents. This includes the theory of method validation, experimental design and practical exercises to reinforce the theory.
  • Review of analytical method reports and scientific papers. Before a report or paper is published, we can review it and make suggestions for possible improvement. This is based on over twenty years of writing reports, publishing papers and refereeing papers for scientific journals.